The IL1R2 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to IL1R2. This antibody recognizes Homo Sapiens, and Human antigen. The IL1R2 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors